LOS ANGELES - Rafael Furcal singled in the go-ahead run to highlight a three-run sixth inning and lift the Dodgers over San Francisco, 4-3.
The defending World Series champions remained winless after losing 2-1 in the teams' season opener a night earlier.
New manager Don Mattingly matched the 2-0 start of mentor and retired Dodgers skipper Joe Torre in 2008.
Chad Billingsley (1-0) allowed three runs and five hits in six innings, struck out four and walked one.
Jonathan Broxton pitched a perfect ninth to earn his second save.
Jonathan Sanchez (0-1) gave up four runs - two earned - and seven hits in 5 2-3 innings, struck out eight and walked three.
MARINERS 6, A'S 2
OAKLAND, Calif. (AP) - Felix Hernandez found his Cy Young form in a hurry, pitching a five-hitter for his 14th career complete game and the first in the majors this year as Seattle beat Oakland.
Chone Figgins hit a go-ahead homer in the sixth inning off Craig Breslow (0-1).
Ichiro Suzuki drove in a run and stole two bases as the Mariners won their opener under new manager Eric Wedge to end a five-game skid in Oakland.
Suzuki moved within one hit of tying Edgar Martinez's franchise record of 2,247.
Hernandez (1-0) dazzled after allowing Josh Willingham's two-run homer in the first. The last pitcher to throw a complete game on opening day was Ben Sheets.